In June 2008, he released a song which was originally produced as a remix for David Guetta's "Everytime We Touch". Somehow, Guetta rejected the remix so Axwell took the instrumental of the song, teamed up with Bob Sinclar who brought in vocalist Ron Carroll and together they created "What A Wonderful World".
In August of the same year, Axwell collaborated with an Australian DJ and producer, Dirty South, and released "Open Your Heart".
At the same time, he also remixed "Hometown Glory" by Adele. The remix was released in two versions, "original mix" with more vocals and more club oriented "Remode".
In 2010 Axwell and Dirty South's remix of the song Sweet Disposition by The Temper Trap, received a nomination for the 53rd Grammy Awards in the category for Best Remixed Recording, Non-Classical.